What’s the Best Time of Day to Take Insulin if You Have Type 2 Diabetes?

For those living with type 2 diabetes, managing blood sugar levels is a daily balancing act. For some, this includes taking insulin. 

But one common question that arises is: when is the best time of day to take insulin if you have type 2 diabetes? 

The answer depends on the type of insulin you're using, your lifestyle, your meals, and your individual treatment plan. Here’s a breakdown to help you understand the best timing and why it matters.

Understanding the Types of Insulin

Before discussing timing, it’s helpful to understand the main types of insulin prescribed for type 2 diabetes:

Basal (long-acting) insulin: Works steadily over about 24 hours. Examples include insulin glargine (Lantus), detemir (Levemir), and degludec (Tresiba).

Bolus (rapid- or short-acting) insulin: Taken before meals to manage blood sugar spikes. Examples include insulin lispro (Humalog), aspart (NovoRapid), and regular insulin.

Premixed insulin: A combination of long-acting and short-acting insulin in one dose.

Best Times to Take Insulin for Type 2 Diabetes

1. Long-Acting (Basal) Insulin

For those who take once-daily basal insulin, the timing is often flexible — but consistency is key.

Evening or bedtime is commonly recommended, especially if morning fasting levels are high.

Morning administration may suit those who experience low blood sugar overnight or have issues with remembering a bedtime dose.

Same time every day: Choose a time that you can consistently stick to — whether that’s after brushing your teeth in the morning or before bed.

Tip: Some insulins, like Tresiba, have more flexibility and don’t need to be taken at exactly the same time each day.

2. Mealtime (Bolus) Insulin

If you're on a basal-bolus regimen, rapid-acting insulin is usually taken:

10 to 15 minutes before a meal, or

Immediately after eating, if blood sugar was low beforehand or if meals are unpredictable.

The goal is to match the insulin peak with the post-meal rise in blood sugar.

3. Premixed Insulin

This is usually taken twice daily, around 30 minutes before breakfast and dinner. Timing is crucial, as it contains short-acting components that need to align with meals.

Things to Consider When Timing Your Insulin

Meal Patterns: Regular meal times help you plan insulin doses more effectively.

Exercise Routines: Physical activity can lower blood sugar, so timing around workouts is important.

Sleep Schedule: Avoiding overnight hypoglycaemia is key; some people need adjustments based on their sleeping patterns.

Shift Work or Irregular Schedules: May require a tailored approach with help from your diabetes care team.

Consult Your Healthcare Provider

Everyone’s diabetes journey is different. What works for one person may not suit another. Always consult your GP, diabetes nurse, or endocrinologist before making changes to your insulin routine. They may recommend adjustments based on your HbA1c results, glucose monitoring data, lifestyle, and other medications.

Final Thoughts

The best time to take your insulin depends on the type of insulin you use and your daily schedule. The key is consistency and coordination with meals and activity. Managing type 2 diabetes with insulin may seem daunting at first, but with the right support and routines, it becomes part of everyday life.